Reta vs TRZ - hardly seems worth it?

That claim comes from influencers. To keep muscle, aim for one gram of protein per pound of goal body weight and drop no more than a pound per week. I'm not lifting and I'm in a big deficit, so don't follow my example and you should be okay.

The ability to hold a large deficit without much effort can produce more muscle loss than ordinary dieting. The medication itself does not cause it, but it makes the conditions easy for someone to lose muscle without realizing it. Retatrutide is rumored to spare muscle better, yet it also tends to speed up loss, which is usually more catabolic. Lean mass is not the same as muscle mass. With only twenty pounds left, switching does not seem worthwhile. I moved from tirzepatide to retatrutide after four weeks and have been on it for about eighteen weeks now. The price gap is small, especially at lower doses. Without clearer data on retatrutide's longer-term glucagon effects, tirzepatide still seems less demanding over time.

I ended up adding extra meals because the weight was coming off too quickly and it was difficult to get enough calories in just three sittings. Now I aim for four meals around six hundred calories each. I'll probably stay with tirzepatide and look into adding CJC, IPA, and TESA later once I reach goal to support lifting.

How quickly did the scale move for you?

Some research suggests even lower protein amounts can work for keeping muscle, especially if you already have training experience. That is a relief because I am about to spend a lot on quality steak.