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Three Months Using Several Different Peptides: My Results So Far

28 replies13 peopleJul 12, 2026☆ Follow
Summary

user experiences with retatrutide kpv ghk-cu and related peptides for fat loss skin issues and recovery

One user lost 30 lb on retatrutide while increasing the dose rapidly and reported broad benefits including appetite control and improved blood markers. KPV produced gradual skin improvements after roughly a month. Several participants discussed injection-site reactions from GHK-Cu and ways to combine it with KPV to reduce irritation. Dosing practices and reconstitution choices for nasal and injectable peptides varied widely among the group.

What this discussion establishesWhere people disagree

Participants differed on safe titration speed for retatrutide and on exact ratios when blending KPV with GHK-Cu

Still open

Whether higher retatrutide doses remain tolerable long term or what the best ongoing NAD+ schedule should be

Nothing here is advice.

28 replies · 13 people
NorthBramble10archiveopening postJul 12

After trying several compounds I wanted to post what has worked and what has not from my own use. I am sorting them into a tier list based only on my results. Retatrutide stands at the top. I began it on April 11 and have dropped 30 lb from 205 to 175 at 6 foot. I plan to stay on a maintenance dose indefinitely because it has improved my blood work, curbed hunger, and produced steady fat loss. I started at 1 mg weekly and moved up to 9 mg, though I do not suggest others increase that quickly.

SteadySparrow75archiveJul 12
↳ replying to @NorthBramble10 (opening post)

Solid post. Since you rate KPV highly, have you considered BPC-157? It pairs well with both KPV and the GHK-Cu you already use.

PatientTimber33archiveJul 12
↳ replying to @NorthBramble10 (opening post)

Thanks for the detailed summary. It is helpful to see real reports. Did you run into any redness, bumps, or itching when injecting GHK-Cu?

WarmCompass44archiveJul 12
↳ replying to @NorthBramble10 (opening post)

That is a fast climb on retatrutide. Maybe I should stop worrying about higher amounts. If KPV and GHK-Cu suit you, the combined version might be worth trying next.

SteadySparrow75archiveJul 12
↳ replying to @PatientTimber33

I plan to mix both GHK-Cu and KPV using saline BAC, filter them, and combine into one sterile vial. The goal is to find a workable ratio of 10 mg KPV to 100 mg GHK-Cu so the saline and KPV together cut down on site irritation.

NorthBramble10archiveJul 12
↳ replying to @SteadySparrow75

BPC-157 interests me for possible future injuries or procedures, but I have no current need. I may add it to the next order simply to keep on hand.

NorthBramble10archiveJul 12
↳ replying to @PatientTimber33

Yes, GHK-Cu does not sting much but still triggers histamine reactions, though milder than tesamorelin. With 100 mg vials mixed in 3 ml bac water the stomach sites react badly while glutes cause almost nothing. Delts have also worked well with only brief soreness.

NorthBramble10archiveJul 12
↳ replying to @WarmCompass44

I would not advise copying my titration schedule. I raised the dose each week while watching side effects and settled on what felt right. At 6 mg results were already solid, yet moving to 9 mg increased the rate of loss while still allowing enough food and protein intake.

PatientTimber33archiveJul 12
↳ replying to @NorthBramble10

You have been very helpful with all the details. Thank you again.

CopperAlder51archiveJul 12

Good summary. A 350 mcg subcutaneous dose of Adamax keeps me going all day, so a full milligram seems high. You mentioned using 2-3 mg of Semax, which shows you tolerate more. I only need 1-1.5 mg. Any interest in trying Selank next?

IronLedger90archiveJul 12
↳ replying to @CopperAlder51

A 10 mg Selank kit is due Monday. I intend to mix the vial with 5 ml of BAC and transfer it into a 5 ml nasal spray bottle so each spray delivers roughly 250-300 mcg.

CopperAlder51archiveJul 12
↳ replying to @IronLedger90

Sterile saline is better because BAC can irritate the sinuses. For a short 20-30 day run you can simply keep the solution refrigerated.

ClearAnchor21archiveJul 12
↳ replying to @IronLedger90

BAC will irritate the sinuses. Saline solution is the safer choice.

IronLedger90archiveJul 12
↳ replying to @ClearAnchor21

I meant sterile saline. I already bought a box of 5 ml ampules. I am so used to BAC for everything else that the wrong word slipped out.

NorthQuill51archiveJul 12
↳ replying to @IronLedger90

Besides the saline advice, note that 10 mg in 5 ml yields 200 mcg per 0.1 ml spray. A calculator would help if you want closer to 250-300 mcg.

ClearAnchor21archiveJul 12
↳ replying to @NorthQuill51

Agreed. An intranasal peptide calculator can help work out the right concentration.

IronLedger90archiveJul 12
↳ replying to @NorthQuill51

The actual output will probably fall somewhere between 200-300 mcg anyway. Most nasal spray bottles vary in how much they deliver, so any calculator input is only an estimate.

IronMarble78archiveJul 12

Solid write-up and useful details. Best of luck with the rest of your run.

GreenHarbour50archiveJul 12
↳ replying to @NorthBramble10 (opening post)

I am already on retatrutide and know how well it works. Starting the combined KPV-GHK-Cu product next gives me hope for clearing lifelong psoriasis and easing wrist tendon pain from desk work.

IronHarbour22archiveJul 12

Thanks for the post. What dose and schedule did you follow with KPV, and how many weeks passed before skin changes appeared? I just began using it for occasional eczema and hope for similar improvement.

BrightSparrow36archiveJul 12
↳ replying to @SteadySparrow75

A 20-to-100 ratio of KPV to GHK-Cu matches the common pre-mixed version and avoids stinging for me. Early bruising occurred but has been minor since I switched injection sites to thighs or glutes.

NorthBramble10archiveJul 12
↳ replying to @IronHarbour22

KPV began at 0.5 mg daily and moved to 1 mg daily for the past month. Visible skin benefits appeared after roughly a month and have continued to improve, reducing both facial flakes and dandruff on shirt collars.

IronHarbour22archiveJul 12
↳ replying to @NorthBramble10

Glad it is helping. I am also on retatrutide and agree it works very well. NAD+ gave noticeable energy from the first day.

NorthBramble10archiveJul 12
↳ replying to @IronHarbour22

What schedule are you using for NAD+? I have tried 100 mg daily but may drop to 50 mg because it produces a strong chest rush and raises heart rate. It clearly works, yet the amount may be excessive.

IronHarbour22archiveJul 12
↳ replying to @NorthBramble10

I started low with a short daily loading phase of 25 mg, then moved to 50 mg two or three times per week. Because published protocols differ so much, I am staying conservative.

SteadySparrow75archiveJul 13
↳ replying to @BrightSparrow36

I reconstituted one 10 mg KPV vial with 2 ml saline BAC, used that solution for a second 10 mg KPV vial, then used the combined liquid for a 100 mg GHK-Cu vial. After filtering into a 10 ml vial I added another 3 ml saline BAC. The first 1 mg GHK-Cu dose therefore also delivered about 0.2 mg KPV. The thigh injection felt stronger than usual but produced no marks or bumps so far. I will hold the current daily amount for at least a week before considering an increase.

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Three Months Using Several Different Peptides: My Results So Far · ZyraTrack Community