Stomach effects from these medications including slower gastric emptying are known to improve with time. Problems raising the dose earlier do not always repeat months later. Nausea and similar issues also commonly ease over several months though not in every case. I don't know much about bariatric procedures. In general higher tirzepatide amounts or adding retatrutide might be handled better now than at the start so beginning very low and advancing very slowly is sensible. Most stomach side effects hit hardest at peak blood levels one to two days after an injection. Splitting doses or using smaller amounts more often can therefore support a larger weekly total while keeping discomfort lower. I'm not sure there is a clear benefit to adding low-dose retatrutide over simply raising the tirzepatide amount assuming the last attempt was some time ago. I'm currently using both at 15 mg tirzepatide plus 5 mg retatrutide without major problems though I had earlier issues.
I'm considering trying retatrutide and would like input to avoid any unwise moves. I'm currently using 2.25 mg tirzepatide but couldn't raise it much because of stomach pain near the cardia after my bariatric procedure. My system has adjusted since then and major side effects have faded. Instead of pushing the tirzepatide amount higher I'm thinking of starting retatrutide at a low 0.5 mg level for very gradual adjustment. My metabolism has stayed very sluggish since the surgery. Questions: does this sound risky overall? Could even 0.5 mg be too strong given my earlier stomach sensitivity with tirzepatide? Would injecting it roughly three days after the tirzepatide dose be reasonable? My food choices are mostly balanced though I miss protein targets sometimes and activity is just light daily movement.