Suggestions for adding cagrilintide while on retatrutide

The original poster on low-dose retatrutide twice weekly for binge-eating control reports renewed late-night binges and plans to add 0.25 mg cagrilintide per retatrutide dose. One reply recommends switching entirely to tirzepatide for stronger food-noise reduction or using cagrilintide alone at 0.25 mg after stopping retatrutide. Another user shares success adding roughly 0.24 mg cagrilintide mid-week to 3 mg weekly retatrutide, noting reduced food noise and continued weight loss while preserving some hunger for protein intake.

• Retatrutide alone can lose effectiveness against food noise after initial months
• Cagrilintide is viewed as providing a stronger "braking" effect on appetite
• One approach is to stop retatrutide and start either tirzepatide or cagrilintide monotherapy
• Another approach keeps retatrutide and adds a weekly cagrilintide dose on a different day
• Users report waiting several weeks to assess full effects when introducing cagrilintide

Whether to drop retatrutide entirely in favor of tirzepatide or cagrilintide versus stacking the two peptides

Optimal starting dose, frequency, and titration schedule when combining the two compounds

Nothing here is advice.