Oral Wegovy approved by FDA

Pass

Haven't looked at it yet. Did absorption look decent? We're probably all hooked on the shots anyway lol...

Having more choices available sounds good to me. It's nice seeing weight loss meds reach folks who get nervous about shots. Sure some versions work a lot stronger but we're really just getting started.

It would be interesting to have direct matchup tests between this option and the other compound. Taking twenty five milligrams daily seems to require a greater quantity of the glp one agonist for matching outcomes. The intake schedule matches the tablet version exactly, so this comes across as simply a larger amount of the established product rather than a fresh development.

These haven't gone up against each other in one trial. Separate research shows one pill version gave fourteen percent body weight drop in sixty four weeks while placebo only two percent. The other pill hit eleven percent in seventy two weeks on max dose with placebo at two percent. One shot got fifteen percent in its primary study against two percent placebo and the last one twenty one percent at top dose compared to three percent placebo.

Dealing with nothing in my belly beforehand always slips my mind and feels really tough.

This isn’t new. The existing oral sema has been out since 2019.

I feel the same way. After hitting the upkeep stage those tablet versions could serve as practical straightforward choices. I'd probably handle covering that recurring monthly cost for good since it comes across as reasonable and doable on my end unlike the steeper outlay tied to the direct service. The one snag is this reduced rate serving as an intro deal plus uncertainty over whether the initial level would prove adequate.

Amateurs...

Getting an injection weekly appeals to me more than needing to recall taking medication each day.

I don't think much of it. A few folks I treat take that diabetes version, and they mainly deal with stomach discomfort. Appetite stays the same, though blood sugar control sees some improvement. I'd go with the other choice every time instead of this tablet.

In an investment discussion board someone mentioned a triple agonist compound during its first human trial at a large pharma firm might come as a tablet form. That's just unconfirmed talk though. Among other tablet versions out there one dual target option posted strong mid stage data that topped existing choices by a wide margin with notable body mass drop after roughly three months instead of the much longer span needed for another candidate. Later stage testing has started signing people up from what I gather. A separate outfit is running daily dosing trials on a single receptor agonist at the second stage. Still another firm has a combined molecule in tablet form also at that same stage. Added extra notes about the dual target option. Now pretty excited about that dual target option. Wonder if anyone is already producing it?

Took the tablet form for eight weeks but saw zero effect at all. My weight went up instead.

Maybe the mix lacked whatever extras would shield it from breaking down in stomach acid. That would explain the outcome. The outfit got results close to what shots achieve based on some prior trial stage so they worked out a way past the digestive barrier or maybe the group whose formula they acquired had already done that.

I'm puzzled why folks might pick the tablet form when shots have gone out of date.

Curious whether this pill version might appear in the unregulated market before long. It seems another compound in that category can already be obtained that way, suggesting producers are capable of creating tablet forms. That could simplify getting started for those hesitant around injections or uncertain about preparing the solution themselves, though it has upsides and downsides since simpler entry could lead to broader use.