Retatrutide and resting heart rate

Mine has stayed lower and very consistent throughout my time on it. I've lost 45.6 pounds since mid-June. I lift heavy weights for 21 sets and do an hour of cardio every day, yet my heart rate never climbs above 110 during the cardio sessions.

If you have a fitness watch you already know your usual swings. After the first injection I saw the same swings still happening, just shifted upward by roughly 6 to 8 beats per minute.

It looks like a factor that varies with each person's setup. Even at low amounts I saw a 5-6 bpm rise in resting rate after four weeks total and never went past half a milligram. My HRV dropped further too, so I stopped. Any GLP can push resting rate up for a while, but it seems to settle with longer use. Some data points to high-dose taurine helping bring it down. I added zone-two cardio two months ago and the rate has been falling; last night I saw 46 while on 7 mg of tirzepatide weekly.

Blood pressure is worth watching too. A drop in pressure can push resting heart rate higher to avoid low blood pressure. Trial data so far on cardiovascular results shows no clear link between the higher rate and negative events.

I don't always trust the weight-loss numbers or other claims people post here. My own rate rose 8 bpm at first but after 40 weeks it settled back to a normal 72. The main side effects listed include nausea in 43 percent, a heart-rate increase around 6.7 bpm, and dysesthesia in about 21 percent at the highest dose. The phase-two data showed the resting-rate increase was dose-dependent, peaked near week 24, then moved back toward baseline by weeks 36-48. The glucagon action is thought to raise resting energy use and therefore heart rate.

I saw a rise when I first began, but it faded. It only climbs again when I increase the dose and stays around 80 for a short time before dropping. My usual rate now sits near 60.

Several months in and I've seen no change to my resting rate. I check blood pressure every day with a connected cuff and nothing moves. This is just one set of results though; others do report issues. My numbers sit between 58 and 62.

Mine climbed 10 bpm for about a month. No irregular rhythms or atrial fibrillation showed up even though I had an ablation before and watch closely. It returned to normal and stays steady, though it edges up a little with each dose increase before settling again within a week or so.

It's striking how differently it affects people. Watching both resting rate and blood pressure makes more sense than reacting to any single reading.