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Stack went cloudy

8 replies8 peopleMay 18, 2026☆ Follow
Summary

Why did my mixed peptide stack turn cloudy and gel-like after refrigeration, and what should I do?

The thread shows that combining many different peptides in one vial often leads to thickening and haze because they have mismatched solubility and stability needs. Several users recommend discarding the mixture and avoiding such blends, though a few note that certain subsets like KPV with BPC-157 and TB-500 can coexist. The original poster later tried a smaller Tesa plus ipamorelin mix and saw similar gelling. Advice centers on not mixing in advance and drawing separate reconstitutions into one syringe instead.

What this discussion establishesStill open

Whether the observed gelling permanently damaged the peptides or was only a temporary physical change

Nothing here is advice.

8 replies · 8 people
LevelThistle41archiveopening postMay 18

I prepared a combination of peptides. Each one looked clear after its own reconstitution and remained clear once everything went into a shared vial. Refrigeration for a day caused the liquid to thicken into something more gel-like and slightly hazy. It still draws without trouble into a 32g needle and seems to produce the expected effect. What should I do? Doses were 10mg ipamorelin, 10mg KPV, 10mg bpc157, 10mg tb500, 10mg pe2228 and 50mg tesamorelin. I assume the answer is to discard it but would like to understand why the change occurred.

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PlainTimber78archiveMay 18
↳ replying to @LevelThistle41 (opening post)

did you blend?

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WarmAlder80archiveMay 18
↳ replying to @LevelThistle41 (opening post)

I see no reason to combine those peptides since their solubility demands are distinct and their pH stability doesn't match. I wouldn't inject this mixture and would simply discard it.

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GreySparrow51archiveMay 18
↳ replying to @LevelThistle41 (opening post)

Have you come across any mention that combining everything together inside one container would be smart?

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RustBeacon82archiveMay 18

Did you combine everything inside a single container? They probably didn't get along once mixed that way. I see how someone could decide to whip up their own shining mix, yet what sense does it make to toss in the rest?

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PatientFenwick39archiveMay 18

Mistakes like that happen now and then. I threw out the container immediately and made sure it never occurred again. Those three compounds mix without any trouble. The other two also sit fine together in a single container. I always store the remaining one on its own.

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LevelMarble91archiveMay 18

It gels pretty easily from what I have noticed and might be messing up the mix. I agree with the others not to put so many in a single container. If the aim is fewer injections then drawing everything into one syringe works for me.

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LevelThistle41archiveMay 19

I got rid of the previous solution and mixed up a new one just using the Tesa along with the ipa. I combined fifty milligrams of Tesa plus ten milligrams of ipa into three milliliters. It's becoming thicker now. Did I wreck the whole kit after only a few days?

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KeenKettle50archiveMay 19

STOP MIXING.

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