Wow, I feel awful. After a long hike hunger hit and I ate a full dinner on the day of my weekly shot. Woke up miserable with a burning throat that was probably reflux and such crushing tiredness I passed out on the couch and nearly suffocated my cat. I never learn but the hunger won. Same thing happened when I first started.
This is your reminder to not eat a full meal before bed the day you pin reta.
Summary
Does eating a full meal before bed on retatrutide injection day trigger reflux, fatigue or other side effects?
Some users report severe reflux, exhaustion and near-blackouts after eating heavily the evening of their weekly shot, while others experience no such reaction or even the opposite effect. Strategies mentioned include morning injections with daytime fasting, dosing on an empty stomach, or needing carbs before bed. A few note the side effect lingers even after months at a stable dose.
What this discussion establishes- Heavy meal right before bed on injection day linked to burning throat and extreme tiredness by some
- Morning pinning plus fasting that day used to prevent the problem
- Empty-stomach dosing at night and minimal eating the next day tried as mitigation
- Opposite reaction or no reaction at all reported by others
- Enjoyment of food still possible on reta unlike some other GLP-1 drugs
Whether the reflux/fatigue reaction occurs at all, and whether it improves with time or stable dosing.
Still openWhether spacing shots closer than seven days would reduce the side effect for those who experience it.
Nothing here is advice.
16 replies · 10 people
I do the shot before bed with almost nothing in my stomach and then eat very little or nothing the next day because of this. Still getting the side effect even after months at the same 6 mg dose.
On reta I have to eat carbs before going to sleep.
To skip this exact problem I always inject in the morning and then fast the rest of the day.
I've been lucky and this never happened to me. Since starting reta I've only eaten one full meal, a real cheat meal after four months, and I just kept going until it was all gone. I worried but felt fine afterward. One thing I like about reta is I can still enjoy food, unlike people on tirz who never want anything.
↳ replying to @ClearLantern70
I can handle a full meal fine too. The issue is specifically eating before bed on the day I pin. I knew better but did it anyway because I hadn't eaten all day after the hike, and it turned out to be a terrible idea.
Sounds like waiting seven days between shots isn't working well for you.
I inject these GLP compounds throughout the week, which might explain why food doesn't bother me as much, though I'm not certain. I also take quite a lot of KPV each day and have long seen it as something that shields my stomach. I'm even considering bringing spicy foods back in. My first round with tirz made me lose any interest in spice because of the reflux. Good luck with your efforts!
↳ replying to @SteadySparrow75
Reta has never caused acid reflux for me, though my wife gets it badly with her tirz doses. I've noticed I need to eat something before bed or else I wake up around three in the morning.
↳ replying to @ClearSignal10
Right after beginning tirz, having tums within reach became necessary before bed.
My meals are extremely wholesome so indigestion seems impossible for me. That substance leaves my system totally unaffected even when six gets divided across two injections.
↳ replying to @BrightCompass57
The issue isn't really the meal you ate, but instead the acid that tags along when it returns. You might have the most satisfying bite, yet whatever comes back up carries that sharp acid with it... gross. That said, I notice the KPV seems to ease the whole thing for me. 👍
↳ replying to @SteadySparrow75
She deals with really bad heartburn from the medication. Antacids and plenty of other products were used but they didn't do much good.
↳ replying to @ClearSignal10
I wonder if gradually lowering the amount brings no relief either. What about dividing the intake or moving to something else completely? You strike me as pretty sharp, so I bet you've already checked every common remedy by this point. Best of luck sorting it out. 👍
↳ replying to @SteadySparrow75
Reducing the dosage doesn't appear to be the way forward here. The trouble began almost immediately. I've attempted mixing the substance from multiple sources to check if it would make a difference, but nothing changed. I mentioned trying divided doses instead, yet she refused, and she shows no desire for the alternative compound. She's seeing strong outcomes with this one aside from the stomach acid problem. I suggested trying that particular peptide, but she has zero curiosity about others. So I'm now exploring things such as beneficial bacteria products, various liquid mixes, and beverages. There's a limit to what works if the individual won't cooperate.
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