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Megadosing Wolverine

17 replies11 peopleOct 29, 2026☆ Follow
Summary

What results come from using very high daily doses of BPC and TB blends for multiple injuries?

Users describe running 5-10 mg daily of combined BPC/TB for several weeks and report reduced pain along with faster recovery from tears and chronic joint issues. Some combine it with other peptides like KPV, Cartalax, and growth-hormone secretagogues while tracking personal metrics such as age, weight, and thyroid status. A few note vision changes and improved training tolerance, yet several express concern over unknown long-term risks and high cost.

What this discussion establishesWhere people disagree

Whether microgram-level dosing is simply too low to be useful or whether multi-milligram amounts carry hidden dangers such as hemangiomas or other growths

Still open

What happens after stopping the high-dose protocol and whether MRI-confirmed structural changes actually occur

Nothing here is advice.

17 replies · 11 people
KeenThistle22archiveopening postOct 29

Right now I am trying to help serious injuries in my shoulder, back, knee and ankle. Daily I take 4 mg total of a BPC/TB/Cartalax blend split into two doses, plus 1 mg AOD, Reta, CJC/IPA at night and Tesa in the morning. The growth-hormone peptides are still new so I run five days on and two off. After missing several days because of illness I doubt it set healing back much. What I noticed after three weeks is clearer vision and less pain in the injuries, though range of motion has not changed. I saw videos of doctors using 10 or 20 mg of BPC or BPC/TB and tried 5 mg of each on Sunday, noticing an immediate HUG

KeenThistle22archiveOct 29

I am male, 44, 1.85 m tall and currently 100 kg after losing 46 kg since April. I follow a keto-carnivore OMAD diet and added Reta later. I lift light weights a few times a week because of the injuries, four young kids and work. I also take 125 mcg T4 daily for long-standing hypothyroidism.

SteadyLedger49archiveOct 29

I have used up to 6 mg a day of the wolverine blend for a month after tearing a quad and had no problems except the injury healed unusually fast. The dose was split morning and evening. Others have gone as high as 15 mg a day for ten or twenty days. There is probably a point of diminishing returns but it seems quite high.

PlainAnchor67archiveOct 29

I have a few kits of Cartalax, BPC and TB on the way so I can try megadosing at 5 mg of each daily.

PlainWillow64archiveOct 30
↳ replying to @KeenThistle22

I am doing almost the same stack and eat a lot of ribeye. I had a six-year elbow and forearm issue that stopped heavy lifting; after Wolverine, Cartalax and KPV on a five-on-two-off schedule the injury is about 95 percent gone. I started Reta at 1 mg but stopped after a month because it made hitting protein targets harder. I lift as heavy as I did in my twenties. Tesa and IPA go in before bed after a two-hour fast. I also tried IGF-1 LR3 but plan to drop it after three weeks because reconstituting every other day is tiring and I feel little from it. My T levels came back strong.

KeenThistle22archiveOct 30
↳ replying to @PlainWillow64

We do share some similarities. I cut out all processed foods, whey and bars and eat zero carbs. I feel good but keeping fat intake high every day is tough. CJC and Tesa overlap in action yet the timing between them should keep things fine. My sleep is poor so my levels sit around 450-500. Some injuries like the labral tear will need surgery anyway. I am cautious about IGF-1 LR3 but may try PEG-MGF soon. I reconstitute several vials at once because the higher doses finish them in a few days.

QuietCompass48archiveOct 30
↳ replying to @SteadyLedger49

A friend ran 10 mg of wolverine daily for ten days on chronic hip and knee pain and said his hips felt great. The protocol is expensive to maintain.

PatientFenwick37archiveOct 30

Imagine what 50 mg a day of BPC and TB would do.

PatientFenwick37archiveOct 30
↳ replying to @KeenThistle22

I am starting to wonder if the usual 0.5-2 mg daily recommendations are too low and whether real benefits only appear at 50-100 mg. Just thinking out loud.

KeenThistle22archiveOct 30
↳ replying to @WarmLantern16

There are reports of cancer-protective effects, yet I would worry more about hemangiomas, nodules or stroke risk with higher amounts.

NorthFenwick56archiveOct 30
↳ replying to @KeenThistle22 (opening post)

I have back and hip pain plus arthritis in my right hand that bothers bench pressing. Pinning wolverine straight into the hand at 0.5-1 mg a day cut some of the pain. I tried mixing BPC with Cartalax and got some relief, but TB with Cartalax did not help the hand. I may test 5 mg BPC alone next because it costs less.

WarmCompass27archiveOct 30
↳ replying to @KeenThistle22

Thanks for sharing your age and metrics. I suspect the useful dose range for healing peptides varies with age, weight and possibly gender, so a protocol that works for one person may not suit another. Many recent reports of megadosing sound positive, but without human trials no single approach should be treated as definitive.

KeenThistle22archiveOct 30
↳ replying to @NorthFenwick56

BPC seems cheaper and can probably be pushed higher with continued improvement, while TB may hit a ceiling sooner. I also have post-traumatic arthritis. After the aggressive phase I will get an MRI to check for changes. The improvement in how things feel is clear, though it might not last.

SharpHarbour71archiveOct 30
↳ replying to @KeenThistle22 (opening post)

All I can add is that TB-500 and BPC-157 seem to work better the more I have taken, though my highest daily amount was 2 mg of each. I do not know where the ceiling lies and will watch for your updates.

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