Reta w/ Hypoglycemia?

I used retatrutide for two months and the only lows I ever had happened during that time. I was not eating small meals often; I skipped breakfast and had only small lunch and dinner. With a continuous glucose monitor my readings dropped into the fifties a couple of times. Because she plans to eat regularly and watch her levels she might handle it better. Starting low and slow seems wise. I went up too fast and did not begin at a low dose.

Without knowing why the lows occur, the only safe step is to get a doctor's opinion first, especially at that age when hypoglycemia can be serious. GLP drugs can cause lows, though it is uncommon even in diabetics and rarer still in people without diabetes. Because retatrutide is still in trials there is less safety data than for semaglutide or tirzepatide. Quick searches suggest lows are less frequent with retatrutide than tirzepatide, so it might be safer. Most doctors will not prescribe an unapproved drug, so tirzepatide could be the option to discuss instead. If a doctor who knows the cause of the lows advises against GLP medications, that advice should be followed.

First answer is talk to a real doctor. Second is risk reduction: use very low doses and watch her readings extremely closely. A continuous monitor would be best. I am not sure, but it might be possible to get one without a prescription since it is not a drug. I also have no idea what it would cost.

I agree with the earlier reply that many different things can cause hypoglycemic episodes, so the cause needs to be identified first. Retatrutide might improve some causes but could make others worse. If this were my relative I would say no until more is known about why the episodes happen.