The dopamine and reward-system reset is a great effect. For that reason alone they are worth using.
Wanted to track my experience with retatrutide, mainly for metabolic healing rather than weight loss. I'm 6'3" and 197 lb but would like to drop about 15 lb. I show signs of insulin resistance and metabolic slowdown. After reading a new book that lays out a strong case for these peptides, I started at 0.5 mg every four days. Third shot was yesterday. Today the effects appeared: almost no appetite, had to push myself to eat, food no longer feels rewarding, more eat-to-live than live-to-eat. Also lost interest in alcohol and cannabis the last few days.