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Delayed Reta dose: use current bac water or wait for new supply?

8 replies6 peopleAug 19, 2026☆ Follow
Summary

Should I delay my Reta dose by a few days or use the non-hospital bac water I already have?

Most participants say a short delay is fine since levels drop slowly and the body tolerates gaps. Several advise using whatever bac water is on hand unless there is a known reaction concern. Injection-site redness is discussed separately from full-body skin sensitivity, with the latter seen as dose-related and often improving over time. A few suggest testing the current water alone to check for reactions before committing to a full dose.

What this discussion establishesWhere people disagree

Whether to use the current bac water immediately or wait for a different supply; some prefer to discard the non-preferred water while others see no problem continuing with it.

Still open

Whether filtering the current water would reduce injection-site reactions, and the exact cause of redness that also occurs with NAD+ from the same source.

Nothing here is advice.

8 replies · 6 people
NorthCompass94archiveopening postAug 19

I have another vial arriving today. The next 8 mg shot is scheduled for tomorrow. My new sterile water supply arrives only on Saturday along with a filtering kit I have never used. Should I go ahead with the water I already have and take the full dose on the usual day, or hold off until the new supply shows up and accept being a few days late?

WarmLantern16archiveAug 19

I would lean toward using what you already have unless you have specific worries about it. Has it worked fine for you so far?

LevelThistle44archiveAug 19
↳ replying to @NorthCompass94 (opening post)

For me it really does not matter. I prefer the hospital-grade version but many others use whatever is available. I once skipped eleven days on purpose so levels would drop, then restarted at the same weekly amount. Nothing bad happened. When you resume you might want to split or shift the dose so you are not taking two full amounts only five days apart.

NorthCompass94archiveAug 19
↳ replying to @WarmLantern16

It has been effective, but I get a red raised area at the injection site that stays for about two weeks. The same thing happens with NAD+ so maybe the water is the cause. I have not tested the water by itself. I also have the odd skin pain, which I think comes from increasing the dose too fast or just how my body reacts to this medication. After three weeks at the current level it feels a bit better than the first week but is still noticeable. Antihistamines give some relief.

PlainAlder11archiveAug 19

Reconstitute and take it. I once shifted my schedule when I was three days late because of travel. Just move the day forward or back by one. I ended up six days off before returning to my usual day. What kind of water do you have right now?

SteadySparrow75archiveAug 19
↳ replying to @NorthCompass94

Do you still get the redness when you use the hospital-grade version?

CopperSignal27archiveAug 19
↳ replying to @NorthCompass94

Try injecting a small amount of the water by itself to see if a reaction occurs. That would give a clear answer. Local site reactions happen with these medications in roughly five percent of users. The peptide itself is the more likely trigger. If the redness lasts two weeks and needs medication, switching to a different medication in the same class might be worth considering once you confirm the cause.

NorthCompass94archiveAug 20
↳ replying to @PlainAlder11

I do not think I can name the source yet because I am still new here. The water I have came with the medication.

CopperSignal27archiveAug 21

That distinction makes sense. Site reactions differ from the widespread skin sensitivity. There is little published research on the sensitivity issue. It seems tied to GLP-1 activity because it showed up often in high-dose studies of a related medication. The reason it appears more often with this medication than others is still unclear. It is dose-sensitive for me as well and worsens above certain thresholds. Some people appear to develop tolerance over time. The positive finding is that there is no sign of lasting nerve damage. The local reaction usually stays the same and is managed if it is not severe.

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