Considering stacking sema with reta

I wish that worked for me. I already mentioned cagri in my original post.

I will look through it, thanks.

Really, those doses are quite small. I would like to stay low as well. How long have you been running both compounds together?

I began sema at the start of August and added reta by the end of that month. I increased too quickly at first and got quite ill, so I slowed down. After the holiday I plan to restart at the same sema dose and maybe 0.3 mg reta. I need to regain a few pounds first. Even after being off for a while I still get full after just a few ounces, which I hope changes enough to enjoy the holiday meal.

Some ghrp6 would probably make you want the whole turkey.

Sorry, I missed that part of your post. Cagri left you very tired. Sema can cause similar fatigue for some people. My mom says it makes her foggy and she sleeps a lot. It might still be worth testing since responses differ. Tesa is another option some have found helpful for the last 10-15 pounds along with appetite effects.

I am already on tesa and have noticed slightly more visible abs at 12 percent body fat, though it actually increased my hunger. Thanks for the other ideas anyway.

I am going to give it a try. I took 7 mg reta yesterday and will add 0.25 mg sema partway through the week, then lower the next reta dose to 3-4 mg based on how things go.

Just to check my understanding, are those doses for maintenance now? I have seen others using low amounts once the main loss phase is over because of the other effects reta offers, whereas I am still on 6 mg weekly for active weight loss help.

How did the first 0.25 mg sema dose feel when you added it?

So sema is the test and reta is the dbol? I like the analogy. I guess MOTS-c would be anavar from now on.

No, those are not maintenance doses. I began at 0.25 mg of each back in August when my BMI was already 20-21. I was trying not to lose more weight but wanted the other reported benefits such as neuroprotection and lower inflammation. Many in the weight-loss groups push back against anyone who wants to lower or microdose, claiming it will cause regain, but I have been off for weeks without the problems they warned about. I think the split comes down to whether people view these compounds as tools for broader health or mainly as weight-loss drugs.

Reta is more like tren e.

I will check back if I start coughing.

That is an interesting way to look at it. Thanks for sharing. I would not mind whatever the GLP version of tren is.

Tren e caused me terrible insomnia, and reta did the same. The comparison might be accurate.

I agree. I want to keep reta low year-round for the same reasons you mentioned. Does anyone have tips for adding sema for the first time? I plan to start it in the next few days and want to avoid bad nausea from even 0.25 mg.

The main advice is to begin low and increase very slowly. If it does not seem strong enough, raise by the smallest amount and wait several days. Responses differ, but going too high at once can make you miserable. If 0.25 mg weekly works, stay there until more is needed, then split into smaller doses every few days. I once tried to jump straight to 2-3 mg weekly and regretted it.

I enjoy tren but at mid-50s it is too much now. For your sema I would probably start at 0.5 mg, though even with training three times a week after a test-tren-mast cycle I am still around 25 percent body fat, so lower doses make sense for someone already lean. You will likely end up at 0.5 mg anyway even with the reta on board.

Thanks for the perspective. I will see how 0.25 mg goes but hope to stay at or below 0.5 mg. I am currently on 250 mg trt after an EQ cycle and am in my mid-20s so still enjoying the process.

Any updates on how the stack went? I am interested in the dosing you ended up using and the results.

I am on almost the same schedule, using 0.5 mg sema only when appetite needs extra help, usually every 10 days or so, along with 2 mg reta once weekly. Loss is about a pound a week, which is faster than I want at this stage, so I may lower the sema a bit. I prefer to keep enjoying food rather than drop the reta.

Look into setmelanotide.

I am also on a 2.4 mg wegovy prescription and want to add reta. Should I begin with 0.25 mg or 0.5 mg reta? How did you tolerate the first doses and did you feel sick or nauseated?

Everyone reacts differently, but the most noticeable side effect I had with reta was skin sensitivity that felt like a mild sunburn, more of an ongoing irritation than real pain. It did not appear in the first month, lasted a few months, then disappeared. You could probably begin with the 0.5 mg dose without major issues.

Thanks. Did you notice any heart-rate increase or sleep changes on reta? Any stomach upset from the combination at the start? How has the weight loss been and are you still dropping?

No clear heart-rate or digestion changes. I have lost around 70 pounds total but the scale has been flat for the last few months. Pants are still getting looser so I may still be losing fat. I am not concerned yet and expect to be more active once the weather improves.

Congratulations on the progress. Thanks for sharing the details and please keep updating us on how things go.

I added 0.25 mg sema on Thursday while already on a fairly high reta dose. I had planned to take another 0.25 mg later that week but realized 0.125 mg would have been smarter for the first try. Reta and tirz never left me with a lingering bad feeling, but sema has been rough, especially yesterday afternoon. It was enough that I skipped my usual reta dose last night until I feel better. You can always add more later, but once you pin too much you have to wait it out.