I've dealt with low blood pressure for years. Might retatrutide push it even lower?
Blood pressure on reta
Summary
Does retatrutide lower blood pressure in people who already have low readings, and what options exist if symptoms appear during weight loss?
Users report retatrutide can further reduce already low blood pressure, with symptoms like postural dizziness worsening in heat. One person saw readings drop from 110/70 to 87/65 after nearly 20 kg loss and is considering stopping. Others note weight loss itself is often the main driver, that similar effects occur with other GLP-1 agonists, and that basic checks plus simple measures like fluids or slower standing are first steps before any medical intervention.
What this discussion establishes- Pre-existing low BP can drop further on reta, especially with substantial weight loss
- Postural symptoms such as head rushes on standing are commonly reported
- Hydration, sodium, and rising slowly are suggested non-drug approaches
- Medical review and electrolyte checks advised before adding salt or other remedies
- Stopping the drug risks weight regain; alternatives like cagri are also expected to lower BP
Whether the BP drop will reverse after stopping reta or if it will persist long-term from the weight loss
Nothing here is advice.
11 replies · 6 people
↳ replying to @LevelThistle44
Thanks, I figured as much. Hotter weather lately has made it worse. I'm nearly at goal weight and don't want to quit. Any ideas what to try?
Sodium and fluids may raise plasma volume. Stand up more slowly to cut the head rushes. What were your usual numbers and what are they reading now?
When you say low blood pressure, what readings or symptoms are we talking about? Do you get dizzy or blurred vision when standing? Have you lost a lot of weight recently or is this only since starting reta? Any other meds that affect BP? Are you drinking less since starting? Grab a cheap home monitor if you don't have one, check sitting and standing a few times, and log the numbers. See a doctor and get bloodwork first before adding anything. Home readings will speed that up.
My old normal was 110/70, now it's 87/65. Standing up fast definitely isn't helping.
↳ replying to @LevelAnchor55
The diagnostic questions from the other poster are solid; the more you answer, the closer you'll get to figuring this out.
Those numbers are quite low even for someone who was carrying extra weight. Current weight? You have clear postural symptoms. Still missing answers to several questions so the cause isn't clear. Age? Any heart issues? Reta itself lowers BP and big weight loss lowers it more. At least half the people after bariatric surgery see this, so it should be common on reta too. I've had greyed-out vision on standing for nearly four years after dropping 80 kg and it may stay. Doctor input is still the safest route. Things like compression stockings or BP-raising meds exist if needed, but this doesn't sound bad enough for that. Don't try salt without electrolyte checks first. Drink more if reta has cut your fluids. Fainting and injury is the main risk to watch.
I'm not obese. I only needed to drop about 20 kg because of binge eating, and reta has helped a lot. I'm close to the end but if this keeps up I may have to stop and check if it improves. Would switching to cagri or eloralintide make any difference?
The weight loss is probably the biggest factor in the drop, though reta adds to it. Both cagri and elora are also known to lower BP. Quitting reta to fix this carries a real risk of regaining the weight. Mild postural issues may be the better trade-off for overall health than putting 20 kg back on.
My blood pressure runs extremely low too; they've turned me away from donating blood because of it. Curious about this as well.
I'm more interested in ways to bring high blood pressure down. Weight loss has moved me from 150/90 to around 140/87 after dropping from 98 kg to 84 kg. Before statins become the only option, is there anything else worth trying? Right now I'm on aged garlic extract, celery seed, coq10, pqq, olive leaf, vitamin d3 with mk7, 4000 mg epa fish oil, berberine, akkermansia, and oea. After the next blood test I might still need to consider statins since they could be easier on liver and kidneys than this stack.
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