Not feeling appetite suppression on reta

The title already tells you what to do. Raise the amount. Use the time you saved to search the board and its search tool.

Posted about this elsewhere too. If appetite control is the main goal, reta is not the best choice; tirz handles that better. Since hunger reduction is not a primary action of reta, it should not be the signal for raising the dose. Reta stresses the body more than other GLPs. Just pushing the dose higher until appetite drops is a bad plan and it is concerning how often that advice appears.

Not saying reta lacks benefits or should be avoided. Just that if appetite control is the goal, tirz is stronger at it, but if staying on reta then appetite should not dictate the dose. There is a case for low-dose stacking though. I was on about four and a half milligrams of tirz with solid hunger control but energy stayed lower after the initial fatigue passed. Dropped tirz to three milligrams and added one milligram of reta. Still need a few weeks to judge, but energy feels noticeably better already. Might be worth letting reta build longer before changing anything.

Are you gaining? If not, hold two milligrams for four weeks then raise only if weight is not coming off. Goal is to reach the dose that produces steady loss of at least half a pound a week with tolerable or no sides. No need to rush, follow the standard approach. It is a long process. Once you hit ten to twelve milligrams and still need more, then consider splitting or stacking.

Non-responders group up. Started at two eighteen, diet and exercise took me to two hundred then a long stall. Fifteen weeks on reta up to twelve milligrams, had every side effect except appetite control. First week digestion slowed but hunger stayed strong, plus bad reflux and indigestion. Added cagrilintide with little change. Heart rate and sleep issues finally became too much, total loss only three pounds. Switching to survodutide along with the cag.

On one milligram a week the first four weeks I could tell my stomach was empty and needed calories, sort of hungry but not interested in eating. When I did eat I filled up fast. Now at two point five milligrams a week that feeling is weaker, but sometimes food grosses me out and I stop even if it is pizza. Just another data point.

No sides at all means slow titration should be fairly safe, but watch blood sugar and keep carbs, water, and electrolytes up. Safest move is to hold two milligrams a couple more weeks then go to four if needed. Pinning every three days or adding tirz this early just adds variables.

The issue is trusting the process. Two milligrams for four weeks is the starting dose used in obese subjects, both for sides and metabolic stability. Starting higher does not give more overall benefit from reta. It may increase appetite control and produce a couple extra percent weight loss early from glycogen and water, but over twelve weeks it does not lead to more total loss and the fat lost would be less than with proper titration. Staying too low too long also fails to create the metabolic shifts reta is meant to deliver.

Been on one milligram for two weeks and basically zero appetite. Did not expect any reaction but now I have to remind myself to eat. Everyone is different.

Appetite response varies. At two milligrams mine was mild, just fuller longer than usual. At four milligrams it was stronger for the first four days then back to mild. Lost very little until reaching four milligrams. Planning to go to five or six soon. Trusting the medication will do its work even if early weight loss is slow. Opposed to stacking right now because keeping the ability to eat is part of what makes reta different.

On two milligrams weekly and dropping fat fast. Would not call it full appetite suppression though I do fill up quicker. Food noise is down but I am craving sweets more. Still disciplined with macros.

Titrated up to twelve milligrams and have not lost a pound. Did better on tirz with a little reta added. Might add something again and see what happens.

Was the same way. Early low doses gave excellent appetite control until around two milligrams a week. Food noise has always been well controlled but now at five milligrams the appetite effect is strong again. Only real downside now is exhaustion returning. Eating more makes it worse. Staying here for a while to see how it goes.

Week seven, started at one milligram now at three. No appetite suppression at all. Still, with only kettlebell workouts three days a week I am down eleven pounds. Could probably drop more if hunger were lower and I stopped the beers. It is working though, half to two pounds a week. Notice I fill up faster and feel content after eating. Will hold three milligrams two more weeks then go to four for a month. If four does not help appetite I will consider adding tirz after more research.

Moved to two point five after one month at one milligram because hunger was returning. Been at two point five almost a month and will stay until there is a reason to go higher.

Remember those worries well. Had strong suppression on tirz but when starting reta not much happened until six milligrams. Began in September and saw little until four or five milligrams and worried it would not work, but it did. Only on seven milligrams now and suppression is very strong, changed body shape too. It is almost too strong but I like it. Suppression now feels better than on tirz. It does reduce enjoyment of food though, tastes good at first then quickly not. Cannot be near leftovers because the smell is intense and makes me feel ill. Can only manage small amounts but I like that. Can choose salad and be as happy as with a cheeseburger. That is not willpower, it is reta assisted. Nine months on reta, forty two pounds down, roughly twenty eight to go. One month left and two years total on GLP-1s with one hundred seventeen pounds lost overall.

In the trials you would already have been on two milligrams for a month and moving to four now. Starting low is fine but staying below the trial starting dose for a month when it is not working is not helpful, and there is no need to add other compounds when you are not near a therapeutic level yet.

Fourth week at five milligrams a week after slow titration from one milligram. Some appetite effect the first week, almost none since week three. Fill up quicker but only a few pounds lost. Not really here for major weight loss and do not see reta as an appetite suppressant. Could lose another ten pounds but no rush. Mostly testing for metabolic reset, better labs, some recomp, and staying lean long term since family health history is poor. Will keep running reta with test and HGH but still hoping for the reta miracle others mention.

Just finished first week on two milligrams and results are good so far. Worried at first about missing the appetite suppression but it showed up quickly and now I can barely eat half my usual amount. Still get hungry but need far less and feel full. Like that it does not make food repulsive. Lost seven pounds but know that includes water and glycogen. Only want a small snack for breakfast and lunch and a small dinner plate. Levels will keep rising over the next month even at the same dose so hopefully tolerance stays low. Happy to stay at the lowest effective dose and ready for loss to slow after the initial drop. Forty year old six foot male, started at two twenty five, two eighteen on first pin and two eleven this morning.