Every few weeks I suddenly crave foods I normally avoid during weight loss, like potstickers, enchiladas, buns, cheese and pie. I put on three or four pounds, notice it in the stomach, and worry the meds have quit working. Then my period arrives and everything reverses quickly, the extra weight drops off in a day or two and appetite returns to normal. You said cycle is not close yet, but bodies can be unpredictable, especially female ones, so a single week may not mean much.
My test subject is on 7.5 tirz with 4 reta right now, along with rotating NAD+, Mots-c or similar. Added TESA for the first time last night. Weight loss stopped this past week and the scale even crept up slightly, after steady 1-2 pound drops each week for months. The bigger issue is strong hunger returning along with heart rate no longer staying up. Only five months total on the two main meds, and it feels like a high dose already, yet results shifted with the same vial. Cycle is still two weeks away.