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Weight loss or Muscle gain?

28 replies14 peopleApr 18, 2026☆ Follow
Summary

how to set a realistic goal weight on GLP-1 meds when creatine, muscle gain, and inaccurate scales complicate the numbers

Users report that starting creatine adds 1-2 kg of lean mass from water retention within two weeks while fat percentage drops. Most advise continuing the supplement and shifting focus from scale weight to fat loss and muscle retention. Goal weight is viewed as a personal choice rather than a fixed ideal derived from BMI or bioimpedance; several suggest aiming for 15-20% body fat instead. Bioimpedance scales are distrusted and DEXA recommended for accurate body-composition tracking.

What this discussion establishesWhere people disagree

whether to push toward a low BMI near 22 or settle around BMI 25-28 with higher muscle mass

Still open

what exact body-fat percentage or final weight each person should target given conflicting scale data

Nothing here is advice.

28 replies · 14 people
PatientThistle39archiveopening postApr 18

Hi everyone. Started GLP-1 last August. Used tirzepatide up to 5 mg weekly for six months then moved over to retatrutide now at 5 mg weekly. Lost roughly 16 kg until four weeks ago when the scale stalled. Tried bumping retatrutide to 6 mg but got bad diarrhea so backed off. Two weeks ago added cagrilintide at 0.12 mg weekly and also began 3 g creatine daily on gym friends advice. The impedance scale now shows weight up about 2 kg yet lean mass rose and body-fat percentage fell. I feel fine but the original aim was weight reduction. Any thoughts on what is going on or similar stories? Should I keep chasing lower scale numbers?

PatientFenwick39archiveApr 18

Creatine adds water inside the muscles so lean-mass numbers go up and the first two weeks are the loading period. That lines up exactly with your timing.

PatientThistle39archiveApr 18
↳ replying to @PatientFenwick39

I already knew creatine does that. The real question is whether to keep taking it or drop it, and what that choice does to the weight-loss target I care about most.

PatientFenwick39archiveApr 18

I would keep the creatine. It helps with lifting and the extra weight is mostly water. The point is dropping fat, not whatever number the scale shows. You could cut off limbs and lose weight too, but that is not the goal.

SteadyBramble67archiveApr 18

We are about the same height and current weight. My watch says 32.5 percent body fat though I do not trust it much. Motivation for the gym is low. Scale weight alone does not tell you about health or how you feel. If the only number that matters is the scale then there are extreme ways to make it drop fast.

PatientFenwick91archiveApr 18

The weight bump lines up with when you started creatine and it has only been a week. Gains from it level off; do not panic unless calories are too high. I dislike the phrase weight loss. Fat loss while keeping or adding lean mass is what counts. Sacrificing muscle is never worth it.

PatientBeacon15archiveApr 18

If the scale is right then you gained muscle and lost fat at the same time. That is a win for health and appearance. I just wish those impedance devices were more trustworthy.

PatientThistle39archiveApr 18

Thanks for the input. I will stay on the current doses for another three or four weeks and keep logging data. Food noise is stronger than it was on tirzepatide so I may raise the retatrutide dose or shorten the interval to six days. The added cagrilintide has not helped much yet.

KeenKettle43archiveApr 30

The app calling you obese is kind of funny.

PatientThistle39archiveMay 1
↳ replying to @KeenKettle43

BMI alone does put me in the obese range at 32. What surprised me more is the ideal-weight figure the app calculated from the other readings. It says 71.3 kg, which would mean another 33-plus kg to lose. I cannot picture weighing that little; last time I was near there I was twelve years old.

CopperSignal27archiveMay 1

The cagrilintide amount tried so far may simply be too small to notice an effect. Testing 0.25 to 0.5 mg would give a clearer picture, but increase slowly. Gut side effects often improve after several months as tolerance builds, so a dose that caused trouble earlier might be fine later. Small steps or splitting doses are safer when retrying retatrutide.

PatientThistle39archiveMay 1
↳ replying to @CopperSignal27

Diarrhea has been manageable lately, maybe thanks to the psyllium I added. Last injection I raised cagrilintide slightly to 0.2 mg while keeping retatrutide at 5 mg. Earlier the bathroom trips were awful, four or five times a night. If things stay settled I will raise both compounds gradually.

PatientThistle39archiveMay 2

How do others on these meds decide on a goal weight versus the ideal weight shown by their scale? I am 180 cm, currently 104 kg, and the device lists 71.3 kg as ideal. Starting weight was 120 kg last July. Reaching the ideal number would mean another 33 kg loss, which feels extreme. Is it better to settle around 80 kg or keep going all the way?

AmberAlder58archiveMay 2

Goal weight is whatever you set for yourself. There is no single correct formula. The real question is what outcome you actually want.

ClearQuill84archiveMay 2

Two things matter most to me: BMI for a rough picture and body-fat percentage. My target is 12-15 percent, down from 29 percent now. It took sixteen months without meds to reach 19 percent body fat two years ago, so the current pace feels doable with retatrutide. BMI is not the main driver.

PatientThistle39archiveMay 2
↳ replying to @AmberAlder58

I agree it is ultimately a personal definition, yet most of us still need some target to stay focused. I originally set 80 kg as the goal, expecting a 40 kg drop over two years. After nine months I am behind that pace and the last two months have been slow, so I am looking for ways to get things moving again.

PatientThistle39archiveMay 2

Congratulations in advance. When you hit the final number you may want to update the nickname.

PatientThistle39archiveMay 2
↳ replying to @ClearQuill84

Aiming at a body-fat percentage makes more sense than BMI. My current reading is 25.3 percent. If the scale is correct, what weight would give me 15 percent body fat? Is it really the 71.3 kg it claims?

ClearQuill84archiveMay 2
↳ replying to @PatientThistle39

It depends on the fat-to-muscle ratio. Someone at 50 percent body fat can share the same BMI as a bodybuilder at 7 percent. Fat weighs less than muscle, so losing fat while adding muscle is the ideal outcome.

CopperSignal27archiveMay 2

If the scale is right and you are at 25 percent body fat now, dropping to 15 percent without losing lean mass would be roughly 10 kg lower, landing around 94 kg or 90-92 kg if some muscle is lost. Those devices only read accurately if you already have a lot of muscle. Waist measurements give a better clue about visceral fat. DEXA or MRI remain the only truly reliable methods.

PatientThistle39archiveMay 2
↳ replying to @ClearQuill84

The scale says I carry 26.5 kg of fat. Reaching the listed ideal weight of 71.3 kg would require losing another 34 kg, which means dropping lean mass too. Either the device is giving a nonsense ideal or I am misunderstanding the numbers.

BlueBramble59archiveMay 2

My original target was 10-15 lb above what I weighed in my thirties. I am now 15 lb below that and still dropping slowly. The new focus is fat loss rather than a fixed scale number. Strength training has been part of the plan the whole time to protect muscle.

GreyMeadow30archiveMay 2

I am also stuck trying to pick a sensible target. Currently 104.3 kg after starting at 114.8 kg in mid-March.

CopperSignal27archiveMay 2

A BMI around 28 at 90 kg and 1.8 m is fine if body fat is 15 percent. Extra muscle does not carry the same health risks as extra fat. Losing another 17 kg of lean tissue just to reach BMI 22 would likely be less healthy. Aiming below 90 kg at 15 percent body fat is quite extreme for most people. Waist size is a useful extra check for visceral fat.

GreenMeadow54archiveMay 2

A DEXA scan is the only way to get trustworthy body-composition data before making big decisions. University exercise-science labs with GE machines tend to be reliable. Impedance scales are too inaccurate to base targets on. For men, 20 percent body fat is healthy, 15 percent is very good, and staying under 12 percent long term is difficult for most.

WarmMeadow92archiveMay 2

I asked my doctor for a goal and she simply said I looked fine. BMI tables suggested 152-205 lb for my height; older insurance tables gave 181-207 lb. A recent DEXA showed 223 lb at 23 percent body fat with a suggested target of 218 lb at 20 percent while adding a little muscle. The scan at least gives clearer direction than the charts.

PatientThistle39archiveMay 2
↳ replying to @CopperSignal27

So you think my original 80 kg target was set too low?

RustCompass19archiveMay 2
↳ replying to @PatientThistle39

The scales are not accurate. DEXA gave me a different body-fat number than the impedance device. If you do not care about the exact percentage you can still use the scale to watch trends. If you want a real number, DEXA is the way. Set staged targets such as first reaching 18-20 percent body fat and calculate weight from there. BMI alone would push me toward an unrealistically low weight given my muscle.

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Weight loss or Muscle gain? · ZyraTrack Community