Been using Reta for about two months. Gained weight initially for a few weeks, then stayed the same for a long time. Probably because I kept raising the dose every week without noticing until around a month later. Once I figured it out, I held at 3mg for a month before going to 4mg. Started thinking maybe it was a dud batch or I screwed up the start, but now I've been dropping weight steadily the past three weeks. I'll stay at 4mg for now to check if that's my sweet spot. Came from Mounjaro which kicked in quicker, so it seems waiting it out was important here.
Retatrutide starting to work!
Summary
How long does retatrutide take to start working for weight loss and what doses seem effective?
Users report initial weight gain or plateau for weeks on reta before steady loss begins, often after slowing titration and holding at 3-4 mg. One person lost 34.8 lbs since mid-June and another saw consistent drops after three weeks at 4 mg following a slow start. Prior Mounjaro users note reta requires more patience. Some worry rapid loss risks muscle while others track by percentage instead of pounds.
What this discussion establishes- Early weeks may involve weight gain or stall before loss starts
- Holding dose at 3-4 mg after quick titration helped some begin losing
- Loss of 34.8 lbs in roughly four months reported by one user
- Combat sports and active jobs can support loss without calorie tracking
- Opinions differ on whether 3 lbs per week is too fast
Whether losing three pounds weekly risks too much muscle loss
Still openWhether 4 mg is an ideal long-term dose for everyone
Nothing here is advice.
9 replies · 8 people
Lost 34.8 pounds since June 16 and looking more defined. Might drop the dose once I shed another 10 pounds so I don't end up too skinny.
↳ replying to @WrySignal55 (opening post)
You often need patience once the early weight comes off with any GLP drug, particularly when you've paused increases because of side effects or worry about them. From what Gemini pulled from studies, tirz averaged 5 to 8 percent loss in the first 12 weeks while reta did 6 to 9 plus percent.
↳ replying to @BrightCompass57
That's quite a bit! Which dose are you on?
↳ replying to @SteadySparrow75
I don't consume a lot, plus combat sports and an active job mean no calorie counting for me. Could be useful but the weight's coming off steadily at the moment. If it stops, maybe I'll start tracking then.
↳ replying to @BrightCompass57
That's three pounds weekly, which is too quick. Don't go without eating or you'll lose muscle, maybe a quarter of it.
↳ replying to @PatientTimber45
Back when I was obese I tracked by percentage instead of pounds. Hard to say the same for everyone here since people vary so much, from those who were heavy with little lifting to bodybuilders using lots of steroids.
Interesting point. I put on weight the first couple weeks too before the loss began. Figured it was just water from inflammation as my body adjusted to the medication.
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