Half-lives / Dihexa

Dihexa half-life

Dihexa stays in your system about 44.2 days — five half-lives at a half-life of ≈ 8.8 days (rat) (212 h). The computed decay curve is below, with the primary source cited.

Also searched as: n-hexanoic-tyr-ile-(6) aminohexanoic amide, pnb-0408.

50% · 9d030d (≈5 half-lives)
Single-dose relative level over time, computed from the published Dihexa half-life (212 h). An estimate from population values — individual pharmacokinetics vary.
Half-life
≈ 8.8 days (rat)
Class
Neuro & cognitive
Route
Research use · animal data only
~97% cleared
44.2 days

Source: PubMed 23055539 (McCoy 2013, J Pharmacol Exp Ther — rat t½ 8.83 days IP / 12.68 days IV; no published human PK)

Frequently asked

How long does Dihexa stay in your system?

With a half-life of ≈ 8.8 days (rat), roughly 97% of a single Dihexa dose is cleared after five half-lives — about 44.2 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 8.8 days (rat) half-life mean in practice?

Every 8.8 days (rat), the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this Dihexa half-life number come from?

PubMed 23055539 (McCoy 2013, J Pharmacol Exp Ther — rat t½ 8.83 days IP / 12.68 days IV; no published human PK). We cite a primary source for every half-life we publish and version every change.

Related: Dihexa reconstitution calculator · Dihexa dose charts

Guides mentioning Dihexa

See your own estimated levels

The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.

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