Half-lives / TB-500

TB-500 half-life

TB-500 stays in your system about 12.5 days — five half-lives at a half-life of ≈ 2–3 days (60 h). The computed decay curve is below, with the primary source cited.

Also searched as: tb500, tb4, thymosin beta-4.

50% · 3d013d (≈5 half-lives)
Single-dose relative level over time, computed from the published TB-500 half-life (60 h). An estimate from population values — individual pharmacokinetics vary.
Half-life
≈ 2–3 days
Class
Recovery, repair & longevity
Route
SubQ · 2×/week
~97% cleared
12.5 days

Source: Thymosin β4 pharmacokinetic literature (see monograph)

Frequently asked

How long does TB-500 stay in your system?

With a half-life of ≈ 2–3 days, roughly 97% of a single TB-500 dose is cleared after five half-lives — about 12.5 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 2–3 days half-life mean in practice?

Every 2–3 days, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this TB-500 half-life number come from?

Thymosin β4 pharmacokinetic literature (see monograph). We cite a primary source for every half-life we publish and version every change.

Related: TB-500 reconstitution calculator · TB-500 dose charts

Related half-lives

Other Recovery, repair & longevity — how long each stays active:

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Guides mentioning TB-500

See your own estimated levels

The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.

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