Half-lives / SS-31 (Elamipretide)

SS-31 (Elamipretide) half-life

SS-31 (Elamipretide) stays in your system about 20 hours — five half-lives at a half-life of ≈ 4 h (4 h). The computed decay curve is below, with the primary source cited.

Also searched as: ss31, elamipretide, forzinity, mtp-131.

50% · 4h020h (≈5 half-lives)
Single-dose relative level over time, computed from the published SS-31 (Elamipretide) half-life (4 h). An estimate from population values — individual pharmacokinetics vary.
Half-life
≈ 4 h
Class
Recovery, repair & longevity
Route
SubQ · research
~97% cleared
20 hours

Source: Elamipretide (SS-31) SubQ PK ≈ 4 h; FDA accelerated approval 2025 (Barth syndrome)

Frequently asked

How long does SS-31 (Elamipretide) stay in your system?

With a half-life of ≈ 4 h, roughly 97% of a single SS-31 (Elamipretide) dose is cleared after five half-lives — about 20 hours. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 4 h half-life mean in practice?

Every 4 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this SS-31 (Elamipretide) half-life number come from?

Elamipretide (SS-31) SubQ PK ≈ 4 h; FDA accelerated approval 2025 (Barth syndrome). We cite a primary source for every half-life we publish and version every change.

Related: SS-31 (Elamipretide) reconstitution calculator · SS-31 (Elamipretide) dose charts

Related half-lives

Other Recovery, repair & longevity — how long each stays active:

Compare all 26 half-lives →

Guides mentioning SS-31 (Elamipretide)

See your own estimated levels

The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.

Open Zyra Track

Zyra Track is a research and educational utility. Nothing on this page is medical advice, a dosing recommendation, or an endorsement of any compound. We never sell or source compounds and refuse sourcing questions. Consult a qualified clinician for decisions about your health.