Articles & guides — page 6

125 cited, vendor-independent pieces on the questions people actually ask — reconstitution and handling, half-lives, compound comparisons, and how to track a protocol. Research and education only; never dosing advice, never sourcing.

125 articles

Compound overviews6 min

What is MK-677 (Ibutamoren)?

MK-677 (Ibutamoren) explained: the oral ghrelin-mimetic that raised GH and IGF-1 in human trials, and the honest catch on appetite, edema and failed endpoints.

Human clinical data
Compound overviews5 min

What is GHRP-6?

GHRP-6 explained: a ghrelin-mimetic hexapeptide that triggers a growth-hormone pulse and a sharp hunger signal, with human GH data but mostly preclinical uses.

Human clinical data
Compound overviews4 min

What is GHRP-2 (Pralmorelin)?

GHRP-2 (Pralmorelin) explained: a ghrelin-mimetic that provokes a growth-hormone pulse — the only GHRP approved anywhere, as a diagnostic test in Japan.

Human clinical data
Compound overviews6 min

What is PT-141 (Bremelanotide)?

PT-141 (bremelanotide) explained from the primary literature: its melanocortin (MC4R) brain mechanism, the phase-3 HSDD trials, and its FDA-approved status.

Approved medicine
Compound overviews6 min

What is Melanotan II?

Melanotan II explained honestly: how this unapproved melanocortin agonist works, and the melanoma, priapism, and nausea signals documented in case reports.

Preclinical
Compound overviews7 min

What is Cagrilintide?

Cagrilintide explained with the human data: the once-weekly amylin analog, how it curbs appetite, and what CagriSema's REDEFINE phase-3 trials showed in obesity and type 2 diabetes.

Human clinical data
Compound overviews5 min

What is AOD-9604?

AOD-9604 explained honestly: the modified growth-hormone fragment marketed for fat loss, its beta-3 lipolysis mechanism in mice, and why its largest human obesity trial missed its primary endpoint.

Human clinical data
Compound overviews5 min

What is HGH Fragment 176-191?

HGH Fragment 176-191 explained honestly: the tail-end piece of growth hormone marketed as a fat-loss peptide, its lipolysis mechanism in animals, and why the human evidence is essentially absent.

Preclinical
Compound overviews5 min

What is tesofensine?

Tesofensine explained with the trial data: a triple monoamine reuptake inhibitor studied for obesity, the 24-week phase 2 results (up to 10.6% weight loss), and its unapproved status.

Human clinical data
Compound overviews4 min

What is SLU-PP-332?

SLU-PP-332 explained with the science: a synthetic pan-ERR agonist studied as an "exercise mimetic" — what it did in mice for metabolism and fitness, and why there is no human data.

Preclinical
Compound overviews4 min

What is 5-amino-1MQ?

5-amino-1MQ explained with the science: a small-molecule NNMT inhibitor that reversed diet-induced obesity in mice by boosting fat-cell metabolism — and why there is no human data.

Preclinical
Compound overviews5 min

What is bimagrumab?

Bimagrumab explained: the anti-ActRII monoclonal antibody that builds muscle while stripping fat, its phase-2 trial results, why it is being paired with GLP-1 drugs, and its status today.

Human clinical data

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