Half-lives / Anastrozole

Anastrozole half-life

Anastrozole stays in your system about 9.6 days — five half-lives at a half-life of ≈ 46 h (46 h). The computed decay curve is below, with the primary source cited.

Also searched as: arimidex, adex.

50% · 46h010d (≈5 half-lives)
Single-dose relative level over time, computed from the published Anastrozole half-life (46 h). An estimate from population values — individual pharmacokinetics vary.
Half-life
≈ 46 h
Class
TRT & hormonal support
Route
Oral · as directed
~97% cleared
9.6 days

Source: FDA label: Arimidex (anastrozole) prescribing information

Frequently asked

How long does Anastrozole stay in your system?

With a half-life of ≈ 46 h, roughly 97% of a single Anastrozole dose is cleared after five half-lives — about 9.6 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 46 h half-life mean in practice?

Every 46 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this Anastrozole half-life number come from?

FDA label: Arimidex (anastrozole) prescribing information. We cite a primary source for every half-life we publish and version every change.

Related: Anastrozole reconstitution calculator · Anastrozole dose charts

Related half-lives

Other TRT & hormonal support — how long each stays active:

Compare all 26 half-lives →

Guides mentioning Anastrozole

See your own estimated levels

The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.

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