Half-lives / Gonadorelin
Gonadorelin half-life
Gonadorelin stays in your system about 2 hours — five half-lives at a half-life of ≈ 10–40 min (0.4 h). The computed decay curve is below, with the primary source cited.
Also searched as: gnrh, lhrh, factrel.
Source: GnRH pharmacology (Belchetz 1978, PMID 100883); terminal half-life 10–40 min
Frequently asked
How long does Gonadorelin stay in your system?
With a half-life of ≈ 10–40 min, roughly 97% of a single Gonadorelin dose is cleared after five half-lives — about 2 hours. Repeated dosing accumulates and takes correspondingly longer to clear.
What does a ≈ 10–40 min half-life mean in practice?
Every 10–40 min, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.
Where does this Gonadorelin half-life number come from?
GnRH pharmacology (Belchetz 1978, PMID 100883); terminal half-life 10–40 min. We cite a primary source for every half-life we publish and version every change.
Related: Gonadorelin reconstitution calculator · Gonadorelin dose charts
Related half-lives
Other TRT & hormonal support — how long each stays active:
Guides mentioning Gonadorelin
See your own estimated levels
The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.
Zyra Track is a research and educational utility. Nothing on this page is medical advice, a dosing recommendation, or an endorsement of any compound. We never sell or source compounds and refuse sourcing questions. Consult a qualified clinician for decisions about your health.