Half-lives / Liraglutide

Liraglutide half-life

Liraglutide stays in your system about 2.7 days — five half-lives at a half-life of ≈ 13 h (13 h). The computed decay curve is below, with the primary source cited.

Also searched as: saxenda, victoza.

50% · 13h03d (≈5 half-lives)
Single-dose relative level over time, computed from the published Liraglutide half-life (13 h). An estimate from population values — individual pharmacokinetics vary.
Half-life
≈ 13 h
Class
GLP-1 & incretin agonists
Route
SubQ · daily
~97% cleared
2.7 days

Source: FDA Saxenda label (NDA 206321); plasma half-life ≈ 13 h (once-daily)

Frequently asked

How long does Liraglutide stay in your system?

With a half-life of ≈ 13 h, roughly 97% of a single Liraglutide dose is cleared after five half-lives — about 2.7 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 13 h half-life mean in practice?

Every 13 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this Liraglutide half-life number come from?

FDA Saxenda label (NDA 206321); plasma half-life ≈ 13 h (once-daily). We cite a primary source for every half-life we publish and version every change.

Related: Liraglutide reconstitution calculator · Liraglutide dose charts

Related half-lives

Other GLP-1 & incretin agonists — how long each stays active:

Compare all 26 half-lives →

Guides mentioning Liraglutide

See your own estimated levels

The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.

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Zyra Track is a research and educational utility. Nothing on this page is medical advice, a dosing recommendation, or an endorsement of any compound. We never sell or source compounds and refuse sourcing questions. Consult a qualified clinician for decisions about your health.